Publications (since 2009)

1. Activated microglia in a rat stroke model express NG2 proteoglycan in
peri-infarct tissue through the involvement of TGF-β1
Kana Sugimoto, Ryutaro Nishioka, Airi Ikeda, Ayano Mise, Hisaaki Takahashi,
Hajime Yano, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka.
Glia 62 185-198(2014)


2. Postnatal interleukin-1β enhances adulthood seizure susceptibility and
neuronal cell death after prolonged experimental febrile seizures in infantile
rats
Mitsumasa Fukuda, Hitomi Hino, Yuka Suzuki, Hisaaki Takahashi, Takehiko
Morimoto, and Eiichi Ishii
Acta Neurologica Belgica (2013)in press


3. Expression of MCP-1 and fractalkine on endothelial cells and astrocytes
may contribute to the invasion and migration of brain macrophages in
ischemic rat brain lesions
Nari Tei, Junya Tanaka, Kana Sugimoto, Tasuku Nishihara, Ryutaro Nishioka,
Hisaaki Takahashi, Hajime Yano, Shirabe Matsumoto, Shiro Ohue, Hideaki
Watanabe, Yoshiaki Kumon, Takanori Ohnishi
J Neurosci Res 91 (2013) 681–693

 

4. Anticonvulsive effect of paeoniflorin on experimental febrile seizures in
immature rats: possible application for febrile seizures in children
Hitomi Hino, Hisaaki Takahashi, Yuka Suzuki, Junya Tanaka, Eiichi Ishii,
Mitsumasa Fukuda
PLoS ONE (2012) 7: e42920. doi:10.1371/journal.pone.0042920

 

5. Zonisamide up-regulated them RNAs encoding astrocytic anti-oxidative and
neurotrophic factors.
Choudhury ME, Sugimoto K, Kubo M, Iwaki H, Tsujii T, Kyaw WT, Nishikawa
N, Nagai M, Tanaka J, Nomoto M,
Eur J Pharmacol 689 (2012) 72–80


6. Premetastatic vasculogenesis in oral squamous cell carcinoma
xenograft-draining lymph nodes.
Mayorca-Guiliani AE, Yano H, Nakashiro KI, Hamakawa H, Tanaka J.
Oral Oncology 48 (2012) 663-670


7. Oct-3/4 promotes migration and invasion of glioblastoma cells.
Kobayashi K, Takahashi H, Inoue A, Harada H, Toshimori S, Kobayashi Y,
Goto K, Sugimoto K, Yano H, Ohnishi T, Tanaka J.
J Cell Biochem 113 (2012) 508-517

 

8. Transient ischemia-induced paresis and complete paraplegia displayed
distinct reactions of microglia and macrophages.
NakataT, Kawachi K, Nagashima M, Yasugi T, Izutani H, Ryugo M, Okamura
T, Shikata F, Imagawa H, Yano H, Takahashi H, Tanaka J.
Brain Res 1420 (2011) 114-124


9. A cytokine mixture of GM‐CSF and IL‐3 that induces a neuroprotective
phenotype of microglia leading to amelioration of (6‐OHDA)‐induced
Parkinsonism of rats.
Choudhury ME, Sugimoto K, Kubo M, Nagai M, Nomoto M, Takahashi H,
Yano H, Tanaka J.
Brain and Behavior 1 (2011) 26-43


10. Subcutaneous injection containing IL-3 and GM-CSF ameliorates stab
wound-induced brain injury in rats.
Tasuku Nishihara, Michihisa Ochi, Kana Sugimoto, Hisaaki Takahashi, Hajime
Yano, Yoshiaki Kumon, Takanori Ohnishi, Junya Tanaka.
Experimental Neurology 229 (2011) 507–516

 

11. Cancer stem-like cells of glioblastoma characteristically express MMP-13
and display highly invasive activity.
Inoue, A., Takahashi, H., Harada, H., Kohno, S., Ohue, S., Kobayashi, K.,
Yano, H., Tanaka, J., Ohnishi, T.
International Journal of Oncology 37 (2010) 1121–1131


12. Iba1+/NG2+ macrophage-like cells expressing a variety of neuroprotective
factors ameliorate ischemic damage of the brain.
Anna Smirkin, Hiroaki Matsumoto, Hisaaki Takahashi, Akihiro Inoue,
Masahiko Tagawa, Shiro Ohue, Hideaki Watanabe, Hajime Yano, Yoshiaki
Kumon, Takanori Ohnishi and Junya Tanaka
Journal of Cerebral Blood Flow & Metabolism (2010) 30, 603–615

 

 

13. Hippocampal interneuron loss in an APP/PS1 double mutant mouse and
in Alzheimer’s disease.
H. Takahashi, I. Brasnjevic, B.P. Rutten, N. Van Der Kolk, D.P. Perl, C.
Bouras, H.W. Steinbusch, C. Schmitz, P.R. Hof and D.L. Dickstein.
Brain Struct. Funct. 214, 145-160 (2010)

 

14. β-hydroxybutyrate alters GABA-transaminase activity in cultured
astrocytes.
Yuka Suzuki, Hisaaki Takahashi, Mitsumasa Fukuda, Hitomi Hino, Kana
Kobayashi, Junya Tanaka, Eiichi Ishii
Brain Research (2009) 1268:17-23


15. The EGFR-GEP100-Arf6-AMAP1 signaling pathway specific to breast
cancer invasion and metastasis
Sabe, H., Hashimoto, S., Morishige, M., Ogawa, E., Hashimoto, A., Nam,
J.-M., Miura, K., Yano, H., Onodera, Y.
Traffic 10 (2009) 982-993


16. Tryptophan 2,3-dioxygenase is a key modulator of physiological
neurogenesis and anxiety-related behavior in mice
Kanai, M., Funakoshi, H., Takahashi, H., Hayakawa, T., Mizuno, S.,
Matsumoto, K., Nakamura, T.
Molecular Brain 2 (2009) art. no. 8